A wonderful article by Charie Stross of Accelerando fame (my favorite SF book in years). It's a wide ranging article which starts with what we know and moves on to where he thinks we might end up in the next few decades.
This quote isn't representative of the article but I liked it so it's what you get. :-)
And then there's a school of thought that holds that, even if AI is possible, the Singularity idea is hogwash — it just looks like an insuperable barrier or a permanent step change because we're too far away from it to see the fine-grained detail. Canadian SF writer Karl Schroeder has explored a different hypothesis: that there may be an end to progress. We may reach a point where the scientific enterprise is done — where all the outstanding questions have been answered and the unanswered ones are physically impossible for us to address.